Lappin & Seymour's Clinical Pharmacokinetics From the Beginning

“I have found this textbook to be a useful desk-side companion, and would recommend to those who are new to pharmacokinetics or wishing for a refresher of key concepts.”

  • elimination rate constant

  • half-life

  • area under the curve

  • absolute oral bioavailability

  • volume of distribution

  • clearance

  • the Rowland equation

  • repeated administration

Calculations are made step-by-step
in the style of a practical do-it-yourself pharmacokinetic workshop. The meaning
of the parameters and their relevance to drug
development are explained.

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There are a series of YouTube videos to accompany the book

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- Drug Metabolism Discussion Group.

“The book I wish I could have read 15 years ago!”

“This book should be essential reading for early career drug discovery and development scientists whose disciplines are impacted by pharmacokinetic data.”

- British Toxicology Society.

“The book will be useful [to the beginner] and at a reasonable cost. The authors set out to self-publish a book that is affordable. In this day of expensive textbooks, this is admirable in the interest of teaching”.

- The Journal of Clinical Pharmacology

- 5 ★ comment on Amazon

In this textbook, the concepts of pharmacokinetics are clearly explained in context with numerous examples of well-established drugs.
The book provides an understand of the origins of clinical pharmacokinetic data and how they are presented. The data are used to calculate:-

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Equations

Download copies of equations, Figures and Tables for educational use (Copyright Lappin & Seymour)

Figures
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